6 potential SARS-CoV-2 vaccine platforms

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Currently, there are 6 potential SARS-CoV-2 vaccine platforms that are being manufactured and tested in animals and/or humans. They are:

  1. mRNA

  2. DNA

  3. Subunit (components [i.e., antigens] of the virus)

  4. Virus-like particles displaying subunits

  5. Whole virus (inactivated) — meaning killed

  6. Whole virus (attenuated) — meaning weakened

Below is a table listing advantages and disadvantages of some of these vaccine platforms that have been developed and are currently in testing for SARS-CoV and MERS-CoV from Prompetchara et al. 2020.

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